Addison's Disease
Contributed By: Donna Hegstrom
W.H.W.T.C.A. Health Committee

Description: Addison's disease results from a failure of the adrenal cortex to produce aldosterone, cortisol and corticosterone. Of the three hormones, the loss of aldosterone is most important clinically. Aldosterone us responsible for maintaining the equilibrium of sodium and potassium in the body.

Clinical Signs: The dog may exhibit varying degrees of anorexia, vomiting, weakness, dehydration, depression and weight loss. Acute episodes may be precipitated by stress and potentially fatal cardiac abnormalities may emerge if the disease is not treated. Age of onset is usually young or middle-aged dogs and is more common in females.

Diagnosis: A complete chemistry profile including blood count and sodium and potassium levels should be completed.

Treatment: Treatment consists of medication and periodic blood work to maintain the appropriate chemical levels in the body.

Mode of Inheritance: Research suggests that the disease often is familial and an autosomal recessive pattern of inheritance has been suggested. This familial tendency frequently is seen when hypoadrenocorticism is associated with other endocrine deficiencies such as hypothyroidism or hypoparathyroidism.



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Any information contained on this site relating to various medical, health, and fitness conditions of Westies and their treatment is for informational purposes only and is not meant to be a substitute for the advice provided by your own veterinarian. You should not use the information contained herein for diagnosing a Westie's health - you should always consult your own veterinarian.


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